Epididymitis

  • ANATOMY OR SYSTEM AFFECTED: Genitalia, reproductive system, skin
  • ALSO KNOWN AS: Epididymo-orchitis

Definition

Acute epididymitis is an inflammation of the epididymis. This is a structure shaped like a tube that surrounds and attaches to each testicle. The epididymis helps transport and store sperm cells.

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Chronic epididymitis causes pain and inflammation in the epididymis. There is often no swelling of the scrotum. Symptoms can last six weeks or more, but this type is less common.

Causes

Epididymitis is most often caused by bacterial infections such as those of the urinary tract, by sexually transmitted infections (STIs) such as chlamydia and gonorrhea, by infection of the urethra (urethritis), by infection of the prostate (prostatitis), and by tuberculosis. Other causes include injury, viral infections such as mumps, genital abnormalities, treatment with the heart rhythm drug amiodarone (Cordarone), and chemotherapy to treat bladder cancer.

Risk Factors

Risk factors for epididymitis include infection of the genitourinary tract (bladder, kidney, prostate, or testicle), narrowing of the urethra, use of a urethral catheter, infrequent emptying of the bladder, recent surgery or instrumentation of the genitourinary tract (especially prostate removal), birth disorders of the genitourinary tract, unprotected sex, and disease that affects the immune system. Most at risk are males ages fifteen to thirty years and men older than age sixty.

Symptoms

Symptoms usually develop within a day and include pain in the testes; sudden redness or swelling of the scrotum; hardness, a lump, or soreness (or all three) in the affected testicle; tenderness in the unaffected testicle; groin pain; chills; fever; inflammation of the urethra; pain during intercourse or ejaculation; pain or burning, or both, during urination; increased frequency of urination; increased pain while having a bowel movement; lower abdominal discomfort; discharge from the penis; and blood in the semen.

Screening and Diagnosis

A doctor will ask about symptoms and medical history and perform a physical exam. Tests may include a urinalysis to check for a high white blood cell (WBC) count and the presence of bacteria; a urine culture to identify the type of bacteria present; a culture of discharge from the penis; a blood test to measure the white blood cell count (WBC); and an ultrasound (a test that uses sound waves to examine the scrotum). Nucleic Acid Amplification Tests (NAATs) and gram stains of urethral secretions may also be used.

Treatment and Therapy

Treatment is essential to prevent the infection from worsening. Treatment may include bed rest. The patient should stay in bed to keep the testicles from moving and to promote healing. Bed rest might be necessary until the swelling subsides. Another treatment is antibiotics, prescribed for bacterial infections. If the patient has an STI, his partners will also need treatment. Another treatment is oral anti-inflammatory medication, which includes drugs such as ibuprofen to help reduce swelling.

The patient may need to wear an athletic supporter for several weeks. Taking baths can ease the pain and help relieve swelling. One should not have sex until treatment is completed. Finally, surgery may be needed in severe cases that return.

Prevention and Outcomes

To help decrease the risk of developing epididymitis, one should practice safer sex. One can protect against STIs by using condoms. Finally, one should empty one’s bladder when feeling the need to do so.

Bibliography

Coward, Matt, and Adam Felman. "Everything You Need to Know About Epididymitis." Healthline, 24 May 2023, www.healthline.com/health/epididymitis. Accessed 10 Nov. 2024.

"Epididymitis." Cleveland Clinic, 1 Oct. 2024, my.clevelandclinic.org/health/diseases/17697-epididymitis. Accessed 10 Nov. 2024.

"Epididymitis - Symptoms and Causes." Mayo Clinic, 6 Apr. 2023, www.mayoclinic.org/diseases-conditions/epididymitis/symptoms-causes/syc-20363853. Accessed 10 Nov. 2024.

Lunenfeld, Bruno, and Louis Gooren, editors. Textbook of Men’s Health. Parthenon, 2007.

Rupp, Timothy J., and Stephen W. Leslie. "Epididymitis - StatPearls." NCBI, 17 July 2023, www.ncbi.nlm.nih.gov/books/NBK430814. Accessed 10 Nov. 2024.

Schrier, Robert W., editor. Diseases of the Kidney and Urinary Tract. 8th ed., Wolters Kluwer Health/Lippincott Williams & Wilkins, 2007.

Simon, Harvey B. The Harvard Medical School Guide to Men’s Health. Free Press, 2004.