Strep throat

Also known as: Streptococcal pharyngitis

Anatomy or system affected: Ears, heart, joints, kidneys, throat

Definition: An acute, contagious, bacterial infection of the throat that often spreads to the ears and sinuses and that can seriously damage the heart and kidneys

Causes and Symptoms

Strep throat is pharyngitis that is caused by a specific strain of streptococcus bacteria. These bacteria are very common and are easily spread by direct, person-to-person contact. Droplets of saliva or nasal mucus from sneezes, coughs, and infected hands, cups, or utensils are frequent means of contact. Young children and teenagers, between the ages of five and fifteen, are at the highest risk. The prevalence of group A Streptococcus ranges from 4 to 20 percent in asymptomatic children under the age of eighteen and from 24 to 37 percent in children with sore throat.

89093560-60345.jpg

After a short incubation period, the bacteria produce definite signs and symptoms: a red sore throat with pain on swallowing, swollen and pus-filled tonsils, enlarged lymph nodes along the jawline and down the neck, and a fever. These symptoms may be milder in younger children less than three years of age, and some may show no symptoms at all. Difficulty in diagnosis may arise from distinguishing strep throat from other bacterial or viral infections.

It is critical, however, to make the diagnosis early. Left untreated, strep infections can have serious consequences for the heart and kidneys. More commonly, the throat problem will spread to the sinuses and ears.

Treatment and Therapy

Strep throat can be differentiated from other throat infections using the technique of sampling (culturing) throat secretions by rubbing the back of the throat with a swab and testing them with special substances that detect this specific strain of bacteria. Testing methods in the twenty-first century provide results in a few hours, instead of days.

Supportive care through increased fluid intake, warm salt-water gargles, throat lozenges, the use of a humidifier, and pain- and fever-reducers such as acetaminophen and ibuprofen are recommended. Antibiotics such as penicillin and erythromycin are the drugs of choice once a definitive diagnosis of strep throat has been made. Symptoms generally subside within a few days. The most feared complication of strep throat is its spread through the blood to the joints and heart, causing rheumatic fever, and to the kidneys, causing glomerulonephritis. Rheumatic fever can seriously and permanently damage the heart valves, while glomerulonephritis can result in kidney failure. Before the development of antibiotics, many children suffered these complications.

Bibliography

Biddle, Wayne. A Field Guide to Germs. 3rd ed. Anchor, 2010.

Centers for Disease Control and Prevention. "Strep Throat: All You Need to Know." U.S. Department of Health & Human Services, 6 Jan. 2023, www.cdc.gov/groupastrep/diseases-public/strep-throat.html. Accessed 15 July 2023.

Children’s Hospital Boston. The Children’s Hospital Guide to Your Child’s Health and Development. Perseus, 2001.

Nathanson, Laura Walther. The Portable Pediatrician. 2nd ed. Quill, 2002.

Shaikh, Nader, Erica Leonard, and Judith M. Martin. "Prevalence of Streptococcal Pharyngitis and Streptococcal Carriage in Children: A Meta-analysis." Pediatrics, vol. 126, no. 3, 2010, pp. E557–64.

Tille, Patricia M. Bailey & Scott’s Diagnostic Microbiology. 15th ed. Elsevier, 2022.

Vincent, Miriam T. “Sore Throat—Strep Throat? When to Worry.” Pediatrics for Parents 21.8 (2004): 11–12. MasterFILE Premier. Web. 12 May 2016.