Osrhoene

A territory or country of northwestern Mesopotamia (now in southeastern Turkey, but at its widest extension also including parts of northeastern Syria), bounded on the west by the river Euphrates and on the north by Mount Masius, and commanding two major routes from western to central Asia

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Osrhoene (called Orrhoene by Pliny the Elder) took its name from Urha, the Syriac name for Edessa (now Urfa) its capital, which in turn may be derived from the name of Orhai (Osroes), an Iranian who more or less openly broke away from the Seleucid empire and founded an autonomous state in c 130 BC. The population of Osrhoene was mainly Aramaic, with Greek and Parthian (Iranian) components; its later rulers were generally Arabs. Their kingdom played a prominent part as a buffer between the Roman and Parthian empires, and was claimed as a dependency by both. In 53 BC Abgar (Ariaramnes) II betrayed Crassus to the Parthians, but in AD 116 and 123 Roman clients came into power, under the protection of Trajan and Hadrian respectively: though Hadrian had evacuated Trajan's short-lived Roman province of Mesopotamia, to which Osrhoene must have been loosely attached.