Eczema

ALSO KNOWN AS: Dermatitis

ANATOMY OR SYSTEM AFFECTED: Skin

DEFINITION: An inflammation of the skin.

CAUSES: Genetic sensitivity to irritants (soaps, detergents, rough clothes), allergens (certain foods, pollen, animal dander), and climate or temperature changes

SYMPTOMS: Red, dry, and itchy skin; scaling, thickening, or cracking of skin

DURATION: Often chronic

TREATMENTS: Minimal exposure to irritants, drugs (corticosteroid creams and ointments, antihistamines, antibiotics); in severe cases, oral corticosteroids or phototherapy

Causes and Symptoms

The term eczema refers to a noncontagious inflammation of the skin. Several types of eczema exist, resulting in a range of symptoms that vary in appearance, duration, and severity. The common characteristic, however, is red, dry, and itchy skin. Other symptoms may include scaling, thickening, or cracking of the skin, leading to infections and severe discomfort.

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Atopic dermatitis, the most common form of eczema, is characterized by itchy and cracked skin of the cheeks, arms, and legs. The onset of this chronic type of eczema occurs most often during infancy or childhood, although symptoms may continue into adulthood. The cause of atopic dermatitis unknown but is thought to be at least partly due to a hereditary predisposition to skin sensitivities to various environmental factors. These factors include irritants such as soaps, detergents, and rough clothes; allergens such as certain foods, pollen, or animal dander; and changes in climate or temperature. Other forms of eczema, such as contact dermatitis, have similar environmental causes. Seborrheic eczema, nummular eczema, and dishydrotic eczema may result from a combination of several possible causes.

Emotional factors, such as stress or frustration, may aggravate symptoms. Because most people with eczema are also found to have certain bacteria on the skin, notably Staphylococcus aureus, a bacterial connection is also hypothesized. Some studies have also linked eczema to immune system dysfunction. The condition is also often found in conjunction with hay fever and asthma, although the exact nature of the connection is not known.

If left untreated eczema can cause a variety of complications beyond the characteristic itchiness and dry skin. Repeated itching and scratching can become a habit and cause a condition known as neurodermatitis or lichen simplex chronicus, in which the scratched area of skin becomes thickened and discolored. Scratching may also break the skin and increase the risk of infection. If the eye area is affected by eczema the patient may be at risk of damaging the eyelid through scratching. Eczema can also cause behavioral issues, such as sleep disruption and depression. A link between atopic dermatitis and attention-deficit hyperactivity disorder (ADHD) has been suggested by some studies.

The diagnosis of eczema requires a careful and detailed observation of symptoms. Family and personal medical histories are often useful to determine the presence of allergies or exposure to allergens or irritants. Dermatologists may also use skin biopsies or blood tests to determine a tendency toward elevated allergic or immune response.

Treatment and Therapy

There is no known cure for eczema, as no single cause has been identified. The treatment of eczema involves minimizing exposure to possible causes while at the same time managing symptoms to maintain a high quality of life. Identifying known allergens and irritants specific to the individual is an important first step. Lifestyle changes aimed at avoiding exposure to these possible causes can lower the frequency and duration of symptoms dramatically. Proper skin care to avoid excessive drying of the skin, including the use of moisturizers or creams and minimizing exposure to water, may also help reduce skin irritation. Avoiding scratching of existing irritations and eliminating sources of emotional stress are other ways that patients can lessen the severity of their symptoms. Any scratched areas that have become infected should be referred to a doctor and may require antibiotics.

Dermatologists may prescribe additional treatments, such as corticosteroid creams and ointments, antihistamines (particularly diphenhydramine for serious itching), or antibiotics. In more severe cases, systemic injected or oral corticosteroid treatments, such as prednisone, or phototherapy—the use of ultraviolet (UV) light—may be tried. When other treatments do not work a doctor may prescribe calcineurin inhibitors such as tacrolimus (Protopic) and pimecrolimus (Elidel), which are applied in ointments to help reduce itching and flareups and protect the skin. However, these drugs affect the immune system and carry potentially strong side effects.

Other therapies have been shown to be effective in treating eczema to certain degrees. The practice of wet dressing, which uses topical corticosteroids together with wet bandages has been demonstrated to control symptoms, though it is not always practical outside of a hospital setting. The amount of potentially harmful skin bacteria can be reduced by taking a bath in a diluted bleach solution no more than three times a week. Oatmeal baths may also prove soothing to some individuals. Meditation, relaxation, and behavior modification programs can help deal with itching and scratching as well as stressors that may exacerbate the condition. Stress treatments can also be helpful to those dealing with embarrassment or other emotional complications from eczema.

Bibliography:

"Atopic Dermatitis (Eczema)." Mayo Clinic, 9 May 2023, www.mayoclinic.org/diseases-conditions/atopic-dermatitis-eczema/symptoms-causes/syc-20353273. Accessed 1 Apr. 2024.

Chovatiya, Raj. "Atopic Dermatitis (Eczema)." JAMA, vol. 329, no. 3, 17 Jan. 2023, p. 268, doi:10.1001/jama.2022.21457. Accessed 1 Apr. 2024.

"Eczema." MedlinePlus. US Natl. Lib. of Medicine, Natl. Institutes of Health, 18 Apr. 2016. Web. 6 Apr. 2016.

Fry, Lionel. An Atlas of Atopic Eczema. New York: Parthenon, 2004.

Hellwig, Jennifer. "Eczema." Health Library, Mar. 11, 2013.

National Eczema Society. National Eczema Society, n. d.

Rakel, Robert E., and Edward T. Bope, eds. Conn’s Current Therapy. Philadelphia: Saunders, 2007.

Ring, J., B. Przybilla, and T. Ruzicka, eds. Handbook of Atopic Eczema. 2d ed. New York: Springer, 2006.

Turkington, Carol A., and Jeffrey S. Dover. Skin Deep: An A-Z of Skin Disorders, Treatments, and Health. 3d ed. New York: Checkmark, 2007.

Westcott, Patsy. Eczema: Recipes and Advice to Provide Relief. New York: Welcome, 2000.