Lobectomy

ALSO KNOWN AS: Pulmonary lobectomy, lung lobe removal

DEFINITION: Lobectomy is the surgical removal of a lobe of a lung.

Cancers treated:Lung cancer, most commonly non-small cell lung cancers (NSCLC)

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Why performed: Lobectomy is a surgical procedure used to treat lung cancer when the tumor is limited to one area of the lung. It may also be used to treat bronchiectasis, tuberculosis, lung abscess, localized fungal infections, chronic obstructive pulmonary disease, or blebs associated with emphysema. It is less invasive than a pneumonectomy, which removes the entire lung, but more invasive than a tumor removal using a wedge resection. In the early 2010s, some medical facilities began offering video-assisted thoracic surgery (VATS) as a form of less-invasive lobectomy when the cancer is in its early stages. This was soon followed by robot-assisted thoracoscopic surgery (RATS). VATS and RATS procedures result in fewer post-operative complications than open lobectomy procedures. The choice of procedure type depends on the cancer type, location, size, and whether it has spread.

Patient preparation: Before surgery, studies are performed to check for abnormalities and establish a baseline for postoperative comparison. These studies include a chest X-ray, electrocardiogram (ECG), bleeding time, and blood tests to check kidney function, electrolytes, hemoglobin, oxygen levels, and white blood cell count. Pulmonary function tests are performed to evaluate lung function. A blood sample is also drawn to check the patient’s blood type in case a transfusion is needed during surgery. The patient must not eat or drink for at least eight hours before surgery, and an intravenous (IV) is inserted for fluids and medications. An indwelling urinary catheter may also be inserted so that urine output can be monitored closely during and after the procedure.

Steps of the procedure: When the patient arrives in the operating suite, an arterial catheter may be inserted to monitor the patient’s blood pressure and oxygenation. After the patient is anesthetized, the surgeon makes an into the chest cavity. When the chest cavity is entered, the lung collapses. The surgeon locates and ties off sources of bleeding, spreads the ribs, and exposes the area of the lung for removal. The surgeon removes the affected lung lobe and repairs the vessels and lung passages from where it was removed. The surgeon inserts one or two chest tubes to drain fluid and reexpand the lung. Then, the surgeon closes the chest cavity and applies a sterile dressing.

After the procedure: The patient is typically transferred to the intensive care unit (ICU) and attached to a monitor that displays heart rhythm, blood pressure, and oxygen saturation. These devices help the ICU nurses closely monitor the patient’s condition. The patient receives supplemental oxygen and IV fluids. The nurses check the chest tube drainage frequently to monitor for excess bleeding. The patient is encouraged to turn, cough, breathe deeply, and use an incentive spirometer to prevent pneumonia. Sequential compression devices are attached to the patient’s legs to help prevent blood clots. Most patients who undergo VATS or RATS procedures have shorter recovery periods than those who undergo open lobectomy.

Risks: The most common complication associated with a lobectomy is a prolonged air leak, which requires a chest tube to be placed for several days. Other risks include surgical site infection, bleeding, pneumonia, hemorrhage, heart problems, blood clots, and respiratory failure. Some research suggests open lobectomy procedures result in an increased risk of complications.

Results: Pathologic examination of the lung specimen reveals the type of cancer. When a lobectomy is performed on early-stage lung cancer, long-term survival is likely. The five-year survival rate is around 70 percent.

Bibliography

Baik, Peter. "Lobectomy." City of Hope, 8 Jan. 2023, www.cancercenter.com/cancer-types/lung-cancer/diagnosis-and-detection/lobectomy. Accessed 20 June 2024.

Batihan, Güntug. Essentials of Pulmonary Lobectomy. IntechOpen, 2023.

Ben-Ari, Elia. "Lung-Sparing Surgery Is Effective for Some with Early-Stage Lung Cancer." National Cancer Institute, 9 Mar. 2023, www.cancer.gov/news-events/cancer-currents-blog/2023/early-stage-lung-cancer-sublobar-surgery. Accessed 20 June 2024.

Cao, Christopher, et al. "Cross-Sectional Survey on Lobectomy Approach (X-SOLA)." Chest, vol. 146, no. 2, 2014, pp. 292–98.

Deslauriers, Jean, F. Griffith Pearson, and Farid M. Shamji. Thoracic Surgery Clinics: Lung Cancer, Part II: Surgery and Adjuvant Therapies, vol. 23, no. 3, 2013, pp. 273–452.

MacRosty, Christina R., and M. Patricia Rivera. Lung Cancer: A Comprehensive Guide for the Clinician. Humana Press, 2023.

Rea, Gerardo, and Mohan Rudrappa. "Lobectomy." StatPearls Publishing, National Library of Medicine, 13 Feb. 2023, www.ncbi.nlm.nih.gov/books/NBK553123. Accessed 20 June 2024.

Scott, Walter J. Lung Cancer: A Guide to Diagnosis and Treatment. 3rd ed., Addicus, 2017.