Tobacco-related cancers

DEFINITION: Tobacco-related cancers are malignant tumors that are caused wholly or in part by the direct use of or indirect exposure to tobacco and tobacco-based products.

RELATED CANCERS: There are many types of cancer related to tobacco. The best-known condition associated with tobacco is lung cancer. In the United States, lung cancer is the leading cause of cancer death, with between 80 and 90 percent of these deaths related to tobacco. Other types of cancer related to tobacco include cancers of the bladder, breast, esophagus, kidney, larynx, liver, mouth, nasal cavity, pancreas, pharynx, stomach, and uterus. Tobacco also has been related to endometrial, cervical, and colon cancers, as well as acute myeloid leukemia.

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Tobacco-related products and their risks: Tobacco products include cigarettes and cigars, as well as smokeless tobacco (such as snuff or chew) and pipe tobacco. Interestingly, nicotine is not considered carcinogenic, though it may play a role in cancer. It is the other chemicals in these products, as well as what happens to them when vaporized through the process of smoking, which are troublesome. For instance, the smoke may contain ammonia, carbon monoxide, cyanide, and even formaldehyde. The way the products are used relates somewhat to the types of cancers produced. For instance, lung cancer is more associated with smoking, while the use of smokeless tobacco products is typically linked to cancers of the mouth and throat.

Incidence and statistics: Approximately 40 percent of all cancer diagnoses in the United States were linked to tobacco use, according to a US Centers for Disease Control and Prevention (CDC) Vital Signs Report in 2016. In 2022, the American Cancer Society reported 30 percent of all cancer deaths were linked to smoking. Worldwide, more than eight million people die each year from tobacco use, according to the World Health Organization (WHO). Of those deaths, seven million are related to direct tobacco use, with the remaining million being non-smokers who were exposed to tobacco.

Of the four thousand chemicals in tobacco smoke, more than two hundred are known to be harmful, and around seventy are known carcinogens. It has been established that smoking cessation significantly lowers the risk of developing and dying from cancer. Five years after quitting, the risk of cancer of the mouth, throat, esophagus, and bladder decreases by half. Ten years after quitting, a former smoker's risk of dying from lung cancer is 50 percent less than the risk faced by those who continue to smoke. In addition to cancer, smoking also causes cardiovascular disease, stroke, sudden infant death syndrome (SIDS), and lung diseases such as chronic obstructive pulmonary disease (COPD). Each year in the United States, tobacco-related health problems cost almost $300 billion in care and $156 billion in lost productivity, according to the CDC in 2021. According to the WHO, however, tobacco use has substantially declined in the twenty-first century. One in five adults are believed to be tobacco users worldwide, and this number is down from one in three in 2000.

Bibliography

Armour, Brian S., et al. "Peer Reviewed: State-Level Medicaid Expenditures Attributable to Smoking." Preventing Chronic Disease, vol. 6, no. 3, 2009, www.ncbi.nlm.nih.gov/pmc/articles/PMC2722402. Accessed 3 July 2024.

Chen, George G., editor. Cigarette Consumption and Health Effects. New York: Nova, 2013.

“Common Cancer Sites — Cancer Stat Facts.” SEER Cancer, 2024, seer.cancer.gov/statfacts/html/common.html. Accessed 3 July 2024.

"Harmful Chemicals in Tobacco Products." American Cancer Society, 5 Apr. 2017, www.cancer.org/cancer/cancer-causes/tobacco-and-cancer/carcinogens-found-in-tobacco-products.html. Accessed 22 Jan. 2018.

“Health Topics - Tobacco - Polaris.” CDC, 30 Sept. 2021, www.cdc.gov/policy/polaris/healthtopics/tobacco/index.html. Accessed 3 July 2024.

"Is Any Type of Smoking Safe?" American Cancer Society, 13 Nov. 2015, www.cancer.org/cancer/cancer-causes/tobacco-and-cancer/is-any-type-of-smoking-safe.html. Accessed 22 Jan. 2018.

Koskinen, Charles J., editor. Handbook of Smoking and Health. New York: Nova, 2011.

LaTorre, Giuseppe. Smoking Prevention and Cessation. New York: Springer, 2013.

Niederhuber, John E., et al. Abeloff's Clinical Oncology. 5th ed., Philadelphia: Saunders, 2013.

Roth, Jack A., Waun Ki Hong, and Ritsuko U. Komaki, editors. Lung Cancer. 4th ed., Hoboken: Wiley, 2014.

"Smoking & Tobacco Use: Fast Facts." Centers for Disease Control and Prevention, US Department of Health and Human Services, 16 Nov. 2017, www.cdc.gov/tobacco/data‗statistics/fact‗sheets/fast‗facts/index.htm. Accessed 23 Jan. 2018.

"Tobacco." National Cancer Institute, National Institutes of Health, 23 Jan. 2017, www.cancer.gov/about-cancer/causes-prevention/risk/tobacco. Accessed 22 Jan. 2018.

“Tobacco.” World Health Organization (WHO), 31 July 2023, www.who.int/news-room/fact-sheets/detail/tobacco. Accessed 3 July 2024.

“Tobacco Use Declines Despite Tobacco Industry Efforts to Jeopardize Progress.” World Health Organization (WHO), 16 Jan. 2024, www.who.int/news/item/16-01-2024-tobacco-use-declines-despite-tobacco-industry-efforts-to-jeopardize-progress. Accessed 3 July 2024.

US Dept. of Health and Human Services. A Report of the Surgeon General: How Tobacco Smoke Causes Disease. Atlanta: Centers for Disease Control and Prevention, 2010.